Friday, February 28, 2020

Strenght limitation ans challenge of ethically social responsible Coursework

Strenght limitation ans challenge of ethically social responsible business - Coursework Example increases the relationships and independence in all the business sectors and more so in dealing with the customers that are on daily basis generating from the business. Social responsibility issues as well as the ethical concerns are extremely sensitive especially to the managers running the business. Due to some of the pressures they often receive from the groups of interest, public, media coverage, governmental and other legal concerns, the managers ensure that they are solely responsible for any of the developments that are more likely in the social and ethical conducts of their people (Joshua 2000, pg.64). This is commonly challenging especially in the decision making of what and where to apply effectively a certain condition that ought to be in place. If there are any conflicting concerns and situations in the peoples and organizations conducts, then it remains a challenge of where to draw the line and make up for the necessary adjustments of the situation. Social responsibility and the ethical conducts of an individual are thus very important in order to avoid some of the conflicting concerns in ensuring a working business environment. In examining some of the common views of ethics that are standardized in the success of any business, that is how to get to the root causes of the challenges. Diagnosing the strengths that are involved in some of the questionings that involves business and the social ethical responsibility of it is just the beginning of a successful business-working environment. The utilitarianism ethics view whereby an ethical problem is likely to approach the question in considering which of the action course may do the least or rather a good harm. According to John Stuart Mill and Jeremy Bentham, the actions are more likely to categorize in a way that they either make many people satisfied and happy of the outcomes (Bowie 1987, pg.53). Further, they explain that a small number of people could be unhappy but so long as the majority is happy

Tuesday, February 11, 2020

Congenital Adrenal Hyperplasia Term Paper Example | Topics and Well Written Essays - 1250 words

Congenital Adrenal Hyperplasia - Term Paper Example pag,). In humans, the gene coding for 21-hydroxylase is located at the major histocompatibility complex on chromosome 6p21.3. Partial deletions, as well as point missense and nonsense mutations, have been found to cause such chromosomal aberrations (Riepe, et al. 2563). Clinical Presentation Early diagnosis is more difficult in cases of CAH because no physical symptoms are present at birth. Thus, the presence of the condition is missed until the age of puberty is reached, when the expected physical changes are not met. As an individual with CAH ages, ambiguous genitalia, accelerated growth, and premature skeletal maturation are seen, due to excessive adrenal androgen production. In males, enlarged penises are noticed even during pre-puberty. On the other hand, such genital enlargement is seen in females as clitoromegaly. In addition, females with CAH present with oligomenorrhea, hirsutism, absence of secondary sexual characteristics, and/or fertility. Because of these features, femal es with undiagnosed CAH are nurtured as males. Among males, severe cases cause severe symptoms such as failure to thrive, recurrent vomiting, dehydration, hypotension, hyponatremia, hyperkalemia, and shock. However, 11-hydroxylase and 17-alpha-hydroxylase-deficient patients may be hypokalemic, and Electrolyte imbalance is caused by adrenal insufficiency, while hypoglycemia and hypotension results from cortisol deficiency (Haldeman-Englert n. pag.; Wilson n. pag.). Treatment In managing patients with CAH, a comprehensive approach on treatment is needed, since the condition does not only affect the physical, but the emotional and psychological aspects of the patient as well. It should, thus, involve medical therapy, surgical intervention and lifestyle modifications. Medical intervention Primarily, the role of medical intervention is to replace glucocorticoids and mineralocorticoids, as well as to decrease the serum levels of virilizing precursor hormones. However, certain medications are necessary to avoid fatal consequences resulting from the symptoms of adrenal insufficiency (Wilson n. pag.). 1.) Corticoids Physiologically, glucocorticoids and mineralocorticoids released by adrenal glands in response to increased levels of adrenocorticotropin hormone (ACTH) are important in regulating normal glucose and electrolyte levels, respectively. In CAH therapy, glucocorticoids are given to suppress the perpetually elevated ACTH levels and adrenal androgen production, while mineralocorticoid therapy reduces angiotensin II levels that regulate blood pressure. All healthcare providers or caretakers of CAH patients should always have an injectable glucocorticoid at hand in case of rapid decline. These medications are safe, since they are normal products of the body, they do not have contraindications, and they only have minimal drug-drug interactions (Wilson n. pag.). Normally, increased levels of cortisol are apparent among individuals who experience stress or illness. Ho wever, as mentioned above, such response is absent among CAH patients due to lack of enzymes needed to produce cortisol. Thus, among CAH individuals, in cases of stress or illnesses, stress dosages of hydrocortisone (50-100 mg/m2 or 1-2